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Chemotherapy uses drugs to kill cancer cells.The drugs are given by an injection into a vein. This may be into a small arm vein or through a skin-tunnelled central line (e.g. Hickman line or Groshong line) which is a tube placed into the vein in the chest. Usually this is the vein which lies just under your collar bone. Part of the tube runs just under the skin in a ‘tunnel’ to reach the vein. The skin-tunnelled central line, can stay in place for weeks or months if necessary.